Borealin蛋白
WebJul 25, 2014 · However, the chromatin factors that specify the CPC to the centromere remain elusive. Here we show that borealin interacts directly with heterochromatin … Web在本项目中,我们探讨了CDK 蛋白激酶如何调节Aurora B复合物中的Borealin 蛋白的功能,进而调节细胞分裂的正常进行。我们的在实验中证实CDK1能够磷酸化Aurora B复合物 …
Borealin蛋白
Did you know?
WebJan 15, 2024 · 研究发现,Borealin维持其他乘客蛋白在着丝粒的正确定位,纠正不正确的着丝粒附着,这在有丝分裂和细胞分裂期间发挥至关重要的作用[3]。此外,Borealin的表 … Web1ml. 309.00元. P2102-5ml. BeyoMag™ Protein A磁珠. 5ml. 1241.00元. 碧云天研发生产的BeyoMag™ Protein A磁珠 (BeyoMag™ Protein A Magnetic Beads ),也称Protein A免疫 …
WebSep 15, 2024 · Cdh1 binds to regions within the N terminus of borealin that act as a non-canonical degron. Aurora B has also been shown previously to be degraded by the APC/C Cdh1 from late mitosis to G1. Indeed, Cdh1 depletion sustains an Aurora B activity with stable levels of borealin and Aurora B throughout the cell cycle, and causes reduced … WebJun 25, 2015 · 4 以Survivin为靶点的肿瘤治疗策略. 以Survivin为靶点的治疗研究成为当今癌症防治研究的热点,其优势主要体现在: (1)Survivin在组织学分布上具有一定的特异 …
Webborealin 似乎是一个生物名词,译过来是什么意思? ... 我也去答题 访问个人页. 关注. 展开全部. 哺乳动物的一种细胞周期蛋白,抗病毒治疗时可以选择的一种治疗靶点 WebAs such, it acts as a subunit of the chromosomal passenger complex, composed of the mitotic kinase aurora B, borealin and inner centromere protein, and is essential for proper chromosome segregation and cytokinesis. For both biological functions, interaction of survivin's nuclear export signal with the nuclear export receptor chromosome region ...
WebAug 28, 2024 · The Chromosomal Passenger Complex (CPC; consisting of Borealin, Survivin, INCENP and Aurora B kinase) and Shugoshin 1 (Sgo1) are key regulators of chromosome bi-orientation, a process essential for error-free chromosome segregation. Their functions rely on their ability to associate with centromeres. Two histone …
WebLoss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality( Abstract_要旨 ) Yamanaka, Yasunari ... 染色体パッセンジャー … body oil resistant sheetsWebAlgorithm. Algorithm Quick BLASTP (Accelerated protein-protein BLAST) Algorithm blastp (protein-protein BLAST) Algorithm PSI-BLAST (Position-Specific Iterated BLAST) Algorithm PHI-BLAST (Pattern Hit Initiated BLAST) Algorithm DELTA-BLAST (Domain Enhanced Lookup Time Accelerated BLAST) Choose a BLAST algorithm Help. body oil recipes with essential oilsWebJun 7, 2024 · The chromosomes in the oocytes of many animals appear to promote bipolar spindle assembly. In Drosophila oocytes, spindle assembly requires the chromosome passenger complex (CPC), which consists of INCENP, Borealin, Survivin, and Aurora B. To determine what recruits the CPC to the chromosomes and it … glenfiddich where nextWebto analyze Borealin 10–109. To assess the function of Borealin 10–109 in localizing the CPC, we used an siRNA-based complementation approach previously described for INCENP (Klein et al., 2006). Endogenous Borealin was depleted from HeLa cells using siRNA duplexes targeting the 30UTR region of the transcript. The knock down of … body oil roll on bottlesWebThe chromosomes in the oocytes of many animals appear to promote bipolar spindle assembly. In Drosophila oocytes, spindle assembly requires the chromosome passenger complex (CPC), which consists of INCENP, Borealin, Survivin, and Aurora B. To determine what recruits the CPC to the chromosomes and its role in spindle assembly, we … glenfiddich whiskey gift setWeb靶向Xklp2靶蛋白(TPX-2)是一个受细胞周期严格调控的细胞核增殖蛋白,参与细胞有丝分裂的纺锤体微管功能,近年研究认为Aurora-B和TPX-2可能在肿瘤形成和进展中有重要促进作用〔5,6〕。本实验检测结肠腺癌组织Aurora-B和TPX-2的表达,分析其临床意义。 1 资料与方法 glenfiddich whisky 18 year old best priceWebCDCA8/Borealin Antibody (1) CDCA8/Borealin antibodies are validated with different applications, which are IHC-P. CDCA8/Borealin cDNA Clone (15) CDCA8/Borealin cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CDCA8/Borealin of different species, especially GFP tag, OFP tag, FLAG … glenfiddich whiskey nz