Dab2 interacting protein

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August undefined, 2024

WebSep 17, 2024 · Meanwhile, the DOC-2/DAB2 interacting protein DAB2IP was previously identified as a member of the Ras-GTPase activating protein family, and functions as a … WebClinVar archives and aggregates information about relationships among variation and human health.

Wnt/β-catenin signaling pathway induces autophagy-mediated

WebFeb 3, 2015 · Dab2 is an adapter protein involved in receptor-mediated signaling, endocytosis, cell adhesion, hematopoietic cell differentiation, and angiogenesis. It plays … WebNX_P49750 - YLPM1 - YLP motif-containing protein 1 - Interactions. Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation. greenbriar cottage florist marshall il

Dab2ip disabled 2 interacting protein [ (house mouse)]

WebOct 18, 2024 · Some GAPs can promote apoptosis of tumor cells to protect the organism. p120RasGAP, regulator of G-protein signaling 3 (RGS3), deleted in liver cancer 1 (DLC1), DOC-2/DAB2 interacting protein (DAB2IP), and STARD13 are typical examples because the five GAPs can influence the balance of antiapoptotic proteins and proapoptotic … WebMay 18, 2010 · The N-terminal half of DAB2IP contains a protein kinase C (see 176960) conserved region-2 (C2) domain and a RasGAP domain. The C-terminal half contains a … WebDescription: Homo sapiens DAB2 interacting protein (DAB2IP), transcript variant 1, mRNA. (from RefSeq NM_032552) RefSeq Summary (NM_032552): DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 … flowers that like afternoon sun

DAB2IP Plays Important Clinical Significance and Correlates With …

NM_001395010.1(DAB2IP):c.1640C>T (p.Thr547Ile) AND not …

WebSep 17, 2024 · Meanwhile, the DOC-2/DAB2 interacting protein DAB2IP was previously identified as a member of the Ras-GTPase activating protein family, and functions as a tumor suppressor in cancer progression 7,8. WebDownload scientific diagram Identi®cation of Dvl-3 as a Dab2-interacting protein. ( A ) Schematic representation of the small-pool cDNA screening strategy using GST±PID. ( B ) Schematic ... flowers that like lots of waterWebOct 6, 2011 · Disabled-2 (Dab2/DOC-2) is a mitogen-responsive adaptor protein required for multiple cellular functions. It is involved in many signaling pathways and plays an integral role in vesicular uptake and trafficking, modulating immune function, protein–protein interactions, cellular homeostasis and differentiation, oncogenesis, and inflammatory ... flowers that like partial shade

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Dab2 interacting protein

WebNX_Q5VWQ8 - DAB2IP - Disabled homolog 2-interacting protein - Function. Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, … WebJan 1, 2024 · DAB2IP, DAB2 Interacting Protein; KIF3a, kinesin family member 3A; RCC, renal cell carcinoma; TCGA, The Cancer Genome Atlas. Discussion. Primary cilium is a microtubule-based structure that protrudes from the centrosomal mother centriole (also known as basal body) into the extracellular milieu [30]. Since cilium axoneme is …

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WebSep 1, 2024 · Mechanistically, DAB2 interacting protein (DAB2IP) was screened as a direct target of miR-1307-3p. The expression of DAB2IP mRNA was down-regulated and … DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcino…

WebDab2IP, also known as apoptosis signal-regulating kinase-interacting protein-1 (ASK1), is a GTPase activating protein associated with aggressive metastatic prostate cancer , … WebJun 25, 2024 · Disabled homolog 2-interacting protein is a new member of the Ras GTPase-activating protein family. 26 The preferred name of DAB2IP is disabled homolog 2-interacting protein, also called ASK-interacting protein 1, ASK1-interacting protein 1, DAB2 interaction protein, DOC-2/DAB2 interactive protein, and nGAP-like protein. …

WebJun 16, 2003 · Identification of Dvl-3 as a Dab2-interacting protein. (A) Schematic representation of the small-pool cDNA screening strategy using GST–PID.(B) Schematic representation of the domain structure of Dvl … WebNov 18, 2016 · The cytoplasmic Ras-GAP protein DAB2IP (Disabled-2 Interacting Protein) is a negative modulator of multiple oncogenic pathways. DAB2IP is rarely mutated, but frequently downregulated or ...

Webdisabled homolog 2-interacting protein, ASK-interacting protein 1, DOC-2/DAB2 interactive protein, DOC2/DAB2 interactive protein GeneRIFs: Gene References Into Functions These findings suggest that Dab-2 is transiently upregulated and phosphorylated (particularly the p96 kDa isoform) in experimental autoimmune encephalomyelitis and …

WebFeb 15, 2024 · Abstract. Disabled-2 (Dab2/DOC-2) is a mitogen-responsive adaptor protein required for multiple cellular functions. It is involved in many signaling pathways and plays an integral role in vesicular uptake and trafficking, modulating immune function, protein … flowers that like lots of sunWebThe 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a … greenbriar cottage florist incWebMy project specifically focused on the potential action of a gene fusion ESR1-Dab2, isolated from metastatic breast cancer patients resistant to … flowers that like part sunWebFeb 15, 2024 · Disabled-2 (Dab2/DOC-2) is a mitogen-responsive adaptor protein required for multiple cellular functions. It is involved in many signaling pathways and plays an integral role in vesicular uptake and trafficking, modulating immune function, protein–protein interactions, cellular homeostasis and differentiation, oncogenesis, and inflammatory … flowers that like full shadeWebApr 1, 2012 · This indicates that the interaction between Dab2 and a DPF-interacting protein is essential for Dab2 function when AP2 levels are low. This DPF-interacting protein is likely FCHO2. While this requirement is only revealed under artificial conditions, its discovery adds to the understanding of the complex interactions occurring within a … flowers that leis are made fromWebRecherche d’alternatives thérapeutiques aux taxanes dans les cancers de la prostate de hauts grades : Identification d’une signature prédictive de la réponse à l’oxaliplatine flowers that like clay soilWebSep 1, 2024 · DAB2 interacting protein (DAB2IP) was screened as a direct target of miR-1307-3p. The expression of DAB2IP. mRNA was down-regulated and inversely correlated with miR-1307-3p level in HCC tissues ... flowers that like wet soil and shade