WebApr 6, 2024 · Cyclin E1 expression in these models was comparable to expression in the HGSOC model CaOv3 which lacks CCNE1 amplification. One BLBC cell line with high … WebHCC1806. Depmap ID: ACH-000624. CCLE Name: HCC1806_BREAST. COSMIC ID: 907047. Sanger ID: 1317. Cell Line Passport: SIDM00875. Cellosaurus RRID: CVCL_1258. Growth Pattern: Adherent. Disease Breast Ductal Carcinoma In Situ Disease Subtype Breast Ductal Carcinoma In Situ ...
An mRNA expression-based signature for oncogene-induced …
Web( A ) HCC1806 cells were transfected with 10 nM of siRNA for 48 h and then treated with 0.5 μM 5-FU for 24 h. The protein expression level of αB-crystallin was evaluated by immunoblotting analysis. α-tubulin was used as the loading control. ( B ) HCC1806 cells were transfected with siRNA for 24 h and then treated with 0.5 μM 5-FU for 24 h. WebMar 21, 2024 · HCC1806: Synonyms: Hcc1806; HCC-1806; Hamon Cancer Center 1806: Accession: CVCL_1258: Resource Identification Initiative: To cite this cell line use: HCC1806 (RRID:CVCL_1258) Comments: Group: Triple negative breast cancer (TNBC) cell line. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line … bulk load in snowflake
Expanding control of the tumor cell cycle with a CDK2/4/6
WebMar 5, 2024 · The human HCC1806 cell line is frequently used as a preclinical model for triple negative breast cancer (TNBC). Given that dysregulated epigenetic mechanisms are involved in cancer pathogenesis, emerging therapeutic strategies target chromatin regulators, such as histone deacetylases. WebMay 31, 2024 · Also remarkably, in the partially resistant HCC1806 cells with strong cyclin E1 expression, p16 was absent due to deletion of the CDKN2A locus (Cosmic database). ... Hennecke S, Amati B (1997) Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins. WebOct 11, 2024 · We describe the pharmacodynamics and efficacy of PF-06873600 (PF3600), a pyridopyrimidine with potent inhibition of CDK2/4/6 activity and efficacy in multiple in … bulk loading dust control