WebLDH can be used as a marker of myocardial infarction, peaking at days 3 and lasting through day 10. Other disorders indicated by elevated LDH include cancer, meningitis, encephalitis, acute pancreatitis, and HIV. … WebLactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells. LDH catalyzes the conversion of lactate to pyruvate and back, as it converts NAD + to NADH and back. A dehydrogenase is an enzyme that …

Lactate Dehydrogenase B Controls Lysosome Activity and ... - PubMed

WebIn a clinically normal 43-year-old male who was found to have low LDH activity in serum by Houki et al. (1986), Sudo et al. (1990) identified a homozygous mutation in the LDHB gene (150100.0001).LDHB mutations have been found in other individuals with LDHB deficiency (see, e.g., 150100.0002-150100.0004). Okumura et al. (1999) tabulated the LDHB … Webreduced LDHB expression and activity. As a control, MCF7 breast cancer cells, characterized by very low LDHB pro-tein expression levels, exhibited marginal LDHB activity (Fig. 2a, b and Supplementary Fig. S2a). Given that LDHB mainly catalyzes the conversion of lactate to pyruvate, we rst investigated whether LDHB activity is important … lda-2e20 エンジンオイル

Frontiers Lactate Dehydrogenase B Is Required for Pancreatic …

Web2 jan. 2011 · Hypoxia and amino acid starvation inhibit mTORC1 activity through TSC1/TSC2-dependent and -independent pathways, respectively . To further ascertain the causative relationship between mTORC1 activation and LDHB expression, we checked the LDHB level in TSC1- or TSC2-null MEFs and the control cells under hypoxia or amino … WebNational Center for Biotechnology Information Webdehydrogenase B (LDHB) is critical for lysosomal activity and autophagy in cancer cells. Silencing LDHB selectively inhibits the proliferation of both oxidative and glycolytic … lda14l-g/k100e/w パナソニック