Phosphopyruvate hydratase
Webphosphoenolpyruvate CHEBI:58702 zoom Cofactor Protein has 1 cofactor binding site: Mg2+ ( UniProtKB Rhea CHEBI:18420 ) Note: Mg 2+ is required for catalysis and for stabilizing the dimer. Pathway Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5. Features Showing features for binding site, active … WebAn enzyme catalyzing the reversible dehydration of 2-phospho-d-glycerate to phosphoenolpyruvate and water; a step in both glycolysis and gluconeogenesis; several …
Phosphopyruvate hydratase
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Web• phosphopyruvate hydratase activity: 細胞組分 • 細胞質 • 細胞質基質 • 細胞膜 • phosphopyruvate hydratase complex • 外排體 • 細胞外空間 • 膜 • photoreceptor inner segment • neuronal cell body • 細胞本體 • 胞內 • myelin sheath: 生物學過程 • 糖質新生 • canonical glycolysis ... Web肺癌是全球常见恶性肿瘤，发病率占第二位，病死率占第一位，预后极差，小细胞肺癌（small cell lung cancer，SCLC）是肺癌一种，源于神经内分泌细胞及支气管黏膜干细胞，患病率占肺癌患者15%~25% [1] 。 依托泊苷联合顺铂（EP）方案化疗是治疗SCLC的标准治疗方案，相比于其他类型肿瘤，SCLC初治化疗 ...
WebEnolase, also known as phosphopyruvate hydratase, is a key glycolytic enzyme in the cytoplasm of prokaryotic and eukaryotic cells. It is a metalloenzyme that requires the … WebThe fumarate hydratase gene, FH, spans 22kb, with ten exons, and encodes two fumarate isoenzymes, cytosolic and mitochondrial. FH catalyzes the conversion of fumarate to malate in the tricarboxylic acid (TCA) cycle.
Web神經元特異性烯醇化酶 （英語： neuron specific enolase ，縮寫 NSE ），也稱為 烯醇化酶2 （enolase 2， ENO2 ）、 γ-烯醇化酶 （Gamma-enolase）是 人類基因組 中編碼的三種 烯醇化酶 （也稱做「磷酸烯醇式丙酮酸水合酶」， phosphopyruvate hydratase）之一，是 小細胞肺癌 和 嗜鉻細胞瘤 的 腫瘤標誌物 。 參考文獻 [ 編輯] ^ 1.0 1.1 1.2 GRCh38: Ensembl … WebPhosphopyruvate Hydratase / metabolism Rats S100 Proteins / immunology Substances Antibodies, Monoclonal Indicators and Reagents Isoenzymes Nerve Tissue Proteins S100 Proteins ...
WebDeficiency of phosphopyruvate hydratase (124618001); Deficiency of 2-phosphoglycerate dehydratase (124618001); Deficiency of enolase (124618001) Definition. A rare, …
WebObjective: To study the diagnostic value of combined detection of 3 tumor markers, namely tissue polypeptide specific antigen (TPS), neuro-specific enolase (NSE) and carcinoembryonic antigen (CEA), in patients with lung cancer. Methods: The serum levels of TPS, NSE and CEA were determined by enzyme-linked immumosorbent assay in 72 … fishtail font free download svgWeb2-Phosphoglyceric acid Tools 2-Phosphoglyceric acid ( 2PG ), or 2-phosphoglycerate, is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate . In glycolysis [ edit] can dried beans be cooked without soakingWebThe PEC antifouling immunosensor based on ZnO/CdSe has a wide linear range (0.10 pg mL -1 -100 ng mL -1) and a low detection limit (34 fg mL -1 ), which has potential application in the clinical diagnosis of small cell lung cancer. MeSH terms Biofouling* / prevention & control Biosensing Techniques* Cadmium Compounds* Electrochemical Techniques fishtail font svgWebSerum neuron-specific enolase (NSE) was measured in 48 newly diagnosed untreated patients with small cell lung cancer (SCLC) by radioimmunoassay. Serum NSE level elevated (greater than or equal to 15 ng/ml) in 50% of all patients. The positive ratio of NSE in patients with extensive disease (64%) wa … fish tail fontsWebMar 7, 2013 · Phosphopyruvate Hydratase. Matt Jacobson, PhD. Thu Mar 7, 2013 . Elisabeth Fall. Professor Research in my lab focuses on atomic-level mechanisms of protein … fishtail font numbersPhosphopyruvate hydratase, usually known as enolase, is a metalloenzyme (EC 4.2.1.11) that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis. The chemical reaction is: 2-phospho-D-glycerate See more In humans there are three subunits of enolase, α, β, and γ, each encoded by a separate gene that can combine to form five different isoenzymes: αα, αβ, αγ, ββ, and γγ. Three of these isoenzymes (all homodimers) are … See more Using isotopic probes, the overall mechanism for converting 2-PG to PEP is proposed to be an E1cB elimination reaction involving … See more Small-molecule inhibitors of enolase have been synthesized as chemical probes (substrate-analogues) of the catalytic mechanism of the … See more • Enolase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more Enolase is a member of the large enolase superfamily. It has a molecular weight of 82,000-100,000 Daltons depending on the isoform. In human alpha enolase, the two subunits are antiparallel in orientation so that Glu of one subunit forms an ionic bond with See more In recent medical experiments, enolase concentrations have been sampled in an attempt to diagnose certain conditions and their severity. For example, higher concentrations of … See more • Holt A, Wold F (December 1961). "The isolation and characterization of rabbit muscle enolase". The Journal of Biological Chemistry. 236 (12): 3227–3231. doi:10.1016/S0021-9258(18)94000-7. PMID 13908561. • Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), … See more can dried beans be frozen after cookingWebGene Ontology Term: phosphopyruvate hydratase complex. GO ID. GO:0000015. Aspect. Cellular Component. Description. A multimeric enzyme complex, usually a dimer or an … fishtail font free svg